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Advia 1800 vs 2120i: Siemens Compared

Every patient sample carries vital information.

These insights can guide treatment decisions, uncover emerging health risks, and ultimately save lives.

To get the most from these samples, labs rely on chemistry and hematology analyzers to turn them into accurate results.

These systems are built to handle everything from routine panels to highly specific tests, all with consistency and speed.

In high-volume hospital labs and specialized research settings, the analyzer you use plays a key role in the accuracy and reliability of test results.

It directly affects the reliability of your results, and the confidence healthcare providers have in making the right decisions for the people they treat.

What is a Chemistry Analyzer?

A chemistry analyzer is a lab instrument designed to measure chemical components in body fluids most commonly blood, plasma or urine.

They analyze everything from glucose and cholesterol to enzymes and electrolytes.

Modern versions are highly automated and can run thousands of tests per hour.

This helps maintain accurate results, providing guide diagnosis and treatment.

They employ techniques such as photometry, ion-selective electrodes (ISE), and turbidimetry to quantify active substances in samples.

There are two main types of chemistry analyzers:

Benchtop Analyzers: Compact models used in small labs or clinics.

High-Throughput Analyzers: Larger systems designed for high-volume testing environments.

What Is a Hematology Analyzer?

A hematology analyzer is a specialized machine that analyzes the cellular components of blood.

Its key use is for conducting complete blood counts (CBCs) which is one of the most commonly ordered tests in medicine.

A CBC provides data on red blood cells (RBCs), white blood cells (WBCs), hemoglobin levels, hematocrit, and platelets.

Hematology analyzers employ tools like flow cytometry, electrical impedance, and light scattering to count and differentiate between different types of blood cells.

Advanced models can even create blood smear slides and perform preliminary morphological analysis, reducing the need for manual review.

These machines are vital for diagnosing conditions such as anemia, infections, leukemias, and clotting disorders.

Why These Analyzers Matter

The accuracy and speed of chemistry and hematology analyzers directly affects patient care.

Faster results lead to quicker diagnoses resulting in timely treatments for better outcomes.

These systems reduce human error, streamline workflows and allow labs to handle larger volumes of samples with less resources.

In today's healthcare environment, turnaround time and precision are essential.

These analyzers are the key to evidence based medical decisions.

Whether it's detecting diabetes, monitoring organ function or identifying blood disorders, these tools ensure physicians get the precise and rapid data they require.

Refurbished Siemens ADVIA 1800 & ADVIA 2120i Analyzers by Diamond Diagnostics

Diamond Diagnostics offers expertly refurbished Siemens ADVIA 1800 Chemistry and ADVIA 2120i Hematology analyzers.

This provides reliable and advanced solutions for laboratories seeking performance without the cost of new equipment.

With rigorous remanufacturing standards and dedicated support, these systems deliver precision, throughput and long-term value.

Overview: Advia 1800 and Advia 2120i

As clinical diagnostics evolve, laboratories depend on precise results, streamlined workflows, and solid reliability to keep patient care on track.

As the pressure to deliver faster turnaround times and manage higher sample volumes grows, the selection of the right system is crucial.

Healthcare facilities offer various systems to help streamline workflows while maintaining analytical accuracy.

The two industry analyzers that have met the complex demands of modern laboratories over other employed tools are the Siemens Advia 1800, a chemistry analyzer, and Advia 2120i, a hematology analyzer.

Though they often appear together in core lab environments, these analyzers serve distinctly different functions.

They are optimized for different aspects of diagnostic testing.

They are also frequently compared when labs consider upgrading or expanding their capabilities to suit different environments.

Siemens Advia 1800 Chemistry Analyzer: Core Functions and Capabilities

The Siemens Advia 1800 is a high performing clinical chemistry analyzer.

It is available in a floor model configuration.

The Advia 1800 is designed for routine and specialized biochemical testing.

It performs quantitative analysis of chemical substances in serum, plasma, urine, cerebrospinal fluid (CSF) and other body fluids.

The Advia 1800 is engineered for high throughput.

This makes it capable of processing up to 1,800 photometric tests/hour.

It supports continuous loading and random access.

This allows labs to process urgent STAT samples without disrupting workflow.

Its broad reagent menu and flexible configuration options minimise human error and improve traceability.

The Advia 1800 is suitable for medium to high-volume laboratories seeking scalability and speed.

Siemens Advia 2120i Hematology Analyzer: Core Functions and Capabilities

The Siemens Advia 2120i is an automated hematology analyzer configured in a bench top setting.

The Advia 2120i performs high resolution blood cell analysis using multi- dimensional flow cytometry and light scatter technology.

It is tailored to analyze whole blood samples efficiently.

It is commonly used in hospitals and core hematology labs.

The Advia 2120i is optimized for complete blood counts (CBCs), white blood cell (WBC), hemoglobin (HGB) and other features.

The analyzer delivers up to 120 CBCs per hour.

Its optional automated slide preparation module helps labs standardize differential slide creation.

It helps to improve the efficiency in high demand hematology settings.

Chemistry vs Hematology: Fundamental Differences in Function

One of the most notable differences between the two systems lies in the type of diagnostics they perform.

Advia 1800Advia 2120i
The Advia 1800 operates in the realm of biochemistry, measuring analyte concentrations in body fluids like serum, plasma, and urine. It relies primarily on photometric and turbidimetric methods. The Advia 2120i performs cellular analysis using blood samples.

They are typically collected in EDTA (Ethylenediaminetetraacetic acid) tubes.

Its diagnostic utility is centered around identifying hematologic abnormalities.

These range from infections and inflammatory responses to anemia and hematologic malignancies such as leukemia.

Workflow and Automation

From a workflow perspective, both systems are built with laboratory automation in mind.

The Advia 1800 features barcoded reagent management, automated sample tracking and connectivity with Laboratory Information Systems (LIS).

It is compatible with various front end automation solutions.

This makes it easy to incorporate into broad lab automation frameworks.

The Advia 2120i also supports the integration of LIS, including intelligent flagging systems, delta checks and integrated quality control management tools.

What sets the 2120i apart is its Unifluidics™ system.

This minimises reagent consumption and reduces maintenance through simplified fluid pathways and automated cleaning routines.

Software, Interface, and Regulatory Compliance

In terms of user interface and software, both systems utilize touchscreen displays and offer customizable reporting formats.

Siemens continually updates the operating software on both systems to reflect growing laboratory standards.

This includes compliance with quality regulations such as CLIA and ISO.

Users can configure calibration schedules and test panels to suit their specific clinical requirements.

The Advia 1800 and 2120i are equipped with an in-built safety feature to help prevent reagent misidentification and cross-contamination.

Maintenance and Operational Considerations

Maintenance varies slightly between the two systems.

Due to its broader reagent panel and frequent calibration needs, the Advia 1800 requires more routine oversight.

This is particularly with photometric and ISE components.

However, it compensates with minimal downtime along with quick changeover procedures for reagents and consumables.

The Advia 2120i, on the other hand, benefits from a more compact internal design and self-cleaning capabilities.

These reduce the frequency of manual maintenance.

The system's intelligent error reporting and diagnostics also help technicians quickly identify and resolve performance issues.

Cost, Scalability and Return on Investment

In terms of finance, both systems represent significant investments.

However, their long term operational savings such as automation, reduced hands-on time and reagent efficiency, can offset upfront costs.

The Advia 1800's higher throughput capacity proves advantageous for labs processing thousands of chemistry tests daily

The Advia 2120i's ability to automate slide preparation can reduce labor costs and improve diagnostic confidence in hematology labs.

Future Proof Technology and Ongoing Support

As of 2025, both analyzers are widely used in hospitals, private diagnostics centers, and academic institutions worldwide.

Siemens' continued support to these platforms from reagent updates to remote monitoring capabilities ensure users stay aligned with the latest diagnostic standards and technological innovations.

Final Words

While both the Siemens Advia 1800 and Advia 2120i reflect high standards of quality and robust engineering, each system is specifically designed to serve distinct areas of laboratory diagnostics.

Choosing between them depends on which one aligns more closely with the clinical focus and testing volume of a laboratory.

For core labs seeking a chemistry solution with unmatched throughput and versatility, the Advia 1800 delivers speed, reliability and efficiency.

For those with a hematology emphasis, the Advia 2120i provides comprehensive cellular analysis and automation in an intelligent, compact package.

Refurbished Siemens Advia 1800 and Advia 2120i analyzers from Diamond Diagnostics offer an exceptional combination of performance, reliability, and value.

Each analyzer is professionally refurbished to OEM standards, undergoing thorough testing, calibration, and quality assurance.

These systems provide a cost-effective alternative to new equipment.

This makes them ideal for laboratories looking to expand capabilities while managing budgets.

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